Prion infection: seeded fibrillization or more?

  title={Prion infection: seeded fibrillization or more?},
  author={Eva Birkmann and Detlev Riesner},
  volume={2 2},
The prion infection is a conversion of host encoded prion protein (PrP) from its cellular isoform PrP(C) into the pathological and infectious isoform PrP(Sc); the conversion process was investigated by in vitro studies using recombinant and cellular PrP and natural PrP(Sc). We present a brief summary of the results determined with our in vitro conversion… CONTINUE READING