Principles of selective inactivation of viral genome. VIII. The influence of beta-propiolactone on immunogenic and protective activities of influenza virus.

Abstract

The influence of beta-propiolactone action on the immunogenic and protective activity of the influenza virus A/WSN/33 (H1N1) has been studied. The production of antibodies against virion surface antigens in mice immunized intramuscularly by the modified virus was enhanced with the increase of inoculating dose from 6 x 10(7) to 1.5 x 10(8) viral particles… (More)

Topics

Cite this paper

@article{Budowsky1993PrinciplesOS, title={Principles of selective inactivation of viral genome. VIII. The influence of beta-propiolactone on immunogenic and protective activities of influenza virus.}, author={E. I. Budowsky and Smirnov YuA and S F Shenderovich}, journal={Vaccine}, year={1993}, volume={11 3}, pages={343-8} }