Principles of rhythmic motor pattern generation.
@article{Marder1996PrinciplesOR, title={Principles of rhythmic motor pattern generation.}, author={Eve Marder and Ronald L. Calabrese}, journal={Physiological reviews}, year={1996}, volume={76 3}, pages={ 687-717 } }
Rhythmic movements are produced by central pattern-generating networks whose output is shaped by sensory and neuromodulatory inputs to allow the animal to adapt its movements to changing needs. This review discusses cellular, circuit, and computational analyses of the mechanisms underlying the generation of rhythmic movements in both invertebrate and vertebrate nervous systems. Attention is paid to exploring the mechanisms by which synaptic and cellular processes interact to play specific roles…
1,259 Citations
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A central pattern generator (CPG) is an assembly of neurons (neuronal network) that produces rhythmic activity without requiring phasic input signals and often drives the motor system and rhythmic…
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The stomatogastric nervous system of decapod crustaceans has contributed significantly to the general principles guiding the present understanding of how rhythmic motor circuits operate at the cellular level.
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The dispute between those who held the more radical view of centrally generated rhythms was resolved conclusively, by demonstrating that neural networks generating rhythmic motor activity can do so in the isolated nervous system, in the absence of the body and therefore sensory feedback.
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All rhythmic motor behaviours are based on central pattern generators, which arise from complex interactions of synaptic and intrinsic neuronal properties governed by diverse types of ion channels.
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