Principles of bound solute dialysis.

  title={Principles of bound solute dialysis.},
  author={John F Patzer},
  journal={Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy},
  volume={10 2},
  • John F Patzer
  • Published 2006 in
    Therapeutic apheresis and dialysis : official…
Toxins that bind to albumin in the bloodstream and are associated with progressing liver failure have proven refractory to removal by conventional hemodialysis. Such toxins can, however, be removed by adding a binder to the dialysate that serves to capture the toxin as it is dialyzed across the membrane. Several approaches based upon this concept are in various stages of clinical evaluation. The thermodynamic basis common to these approaches has been used to develop an engineering description… CONTINUE READING

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