Principles of bioactive lipid signalling: lessons from sphingolipids

@article{Hannun2008PrinciplesOB,
  title={Principles of bioactive lipid signalling: lessons from sphingolipids},
  author={Yusuf A. Hannun and Lina M. Obeid},
  journal={Nature Reviews Molecular Cell Biology},
  year={2008},
  volume={9},
  pages={139-150}
}
  • Y. Hannun, L. Obeid
  • Published 1 February 2008
  • Biology, Medicine
  • Nature Reviews Molecular Cell Biology
It has become increasingly difficult to find an area of cell biology in which lipids do not have important, if not key, roles as signalling and regulatory molecules. The rapidly expanding field of bioactive lipids is exemplified by many sphingolipids, such as ceramide, sphingosine, sphingosine-1-phosphate (S1P), ceramide-1-phosphate and lyso-sphingomyelin, which have roles in the regulation of cell growth, death, senescence, adhesion, migration, inflammation, angiogenesis and intracellular… 
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