Principles of antibiotic penetration into abscess fluid.

@article{Wagner2006PrinciplesOA,
  title={Principles of antibiotic penetration into abscess fluid.},
  author={Claudia Christina Wagner and Robert Sauermann and Christian Joukhadar},
  journal={Pharmacology},
  year={2006},
  volume={78 1},
  pages={1-10}
}
Although drainage is considered the gold standard in abscess treatment, abscesses of different sizes and locations have been successfully cured by means of antibiotic treatment alone. The penetration of an antibiotic into an encapsulated purulent lesion is limited and highly dependent on the degree of abscess maturation. In fact, in vivo pharmacokinetic data demonstrate that substantial antibiotic concentrations can be reached within abscesses in humans and animals, provided the choice of an… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Theoretical approach to local infusion of antibiotics for infected pancreatic necrosis.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] • 2016
View 1 Excerpt

2013 WSES guidelines for management of intra-abdominal infections

World journal of emergency surgery : WJES • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…