Principles of antibiotic penetration into abscess fluid.

  title={Principles of antibiotic penetration into abscess fluid.},
  author={Claudia Christina Wagner and Robert Sauermann and Christian Joukhadar},
  volume={78 1},
Although drainage is considered the gold standard in abscess treatment, abscesses of different sizes and locations have been successfully cured by means of antibiotic treatment alone. The penetration of an antibiotic into an encapsulated purulent lesion is limited and highly dependent on the degree of abscess maturation. In fact, in vivo pharmacokinetic data demonstrate that substantial antibiotic concentrations can be reached within abscesses in humans and animals, provided the choice of an… CONTINUE READING

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