Principles of a switch.

@article{Ptashne2011PrinciplesOA,
  title={Principles of a switch.},
  author={Mark Ptashne},
  journal={Nature chemical biology},
  year={2011},
  volume={7 8},
  pages={
          484-7
        }
}
As a higher organism develops, genes turn on and off—that is, they are transcribed or not—in complicated patterns, often in response to signals sent from other cells1. The bacterial virus (phage) lambda is a model for the study of such phenomena. Lambda’s genes are expressed in two distinct patterns, controlled by its switch. The switch also controls the transition between these patterns in response to an extracellular signal. Just two DNA-binding regulatory proteins and the enzyme RNA… CONTINUE READING
BETA

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-3 OF 3 REFERENCES

Genes and Signals (Cold Spring Harbor Laboratory Press, Cold Spring Harbor

  • M. Ptashne, A. Gann
  • 2002

Similar Papers

Loading similar papers…