Principles of Carbon Catabolite Repression in the Rice Blast Fungus: Tps1, Nmr1-3, and a MATE–Family Pump Regulate Glucose Metabolism during Infection

@inproceedings{Fernandez2012PrinciplesOC,
  title={Principles of Carbon Catabolite Repression in the Rice Blast Fungus: Tps1, Nmr1-3, and a MATE–Family Pump Regulate Glucose Metabolism during Infection},
  author={Jessie Fernandez and Janet D. Wright and David Hartline and Cristian F. Quispe and Nandakumar Madayiputhiya and Richard A Wilson},
  booktitle={PLoS genetics},
  year={2012}
}
Understanding the genetic pathways that regulate how pathogenic fungi respond to their environment is paramount to developing effective mitigation strategies against disease. Carbon catabolite repression (CCR) is a global regulatory mechanism found in a wide range of microbial organisms that ensures the preferential utilization of glucose over less favourable carbon sources, but little is known about the components of CCR in filamentous fungi. Here we report three new mediators of CCR in the… CONTINUE READING
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