Principles of Appropriate Antibiotic Use for Acute Rhinosinusitis in Adults: Background

  title={Principles of Appropriate Antibiotic Use for Acute Rhinosinusitis in Adults: Background},
  author={John M. Hickner and Jack Bartlett and Richard E. Besser and Ralph Gonzales and Jerome Hoffman and Merle A. Sande},
  journal={Annals of Internal Medicine},
1.0 The excessive use of antibiotics in ambulatory practice has contributed to the emergence and spread of antibiotic-resistant bacteria (1-2, 4). Antibiotic treatment of common respiratory infections accounts for a large percentage of this excessive use. Rhinosinusitis is one of the 10 most common diagnoses in ambulatory practice and is the cause of an estimated 25 million U.S. physician office visits in 1995 (5). Fourteen percent of Americans claim to have had a previous diagnosis of… 
Principles of drug therapy for acute bacterial rhinosinusitis: from evidence-based medicine to practice
There exists a wide range of medications for treatment of ABRS in the pharmacological market and some of them do not meet the requirements of evidence-based medicine so far, but they are included to the Russian standards and are used for management of AB RS.
Beginning antibiotics for acute rhinosinusitis and choosing the right treatment
  • E. Wald
  • Medicine, Biology
    Clinical reviews in allergy & immunology
  • 2006
There has been some controversy in the literature regarding the effectiveness of antibiotics in the treatment of ABS, but most studies in which the diagnosis of acute bacterial sinusitis is confirmed with images and appropriate anti-biotics are preseribed show superior outcomes in recipients of antibiotics.
Diagnosis and Management of Acute Rhinosinusitis
There is a paucity of data supporting use of commonly used symptomatic therapies, with the exception of intranasal corticosteroids, which have demonstrated rapid improvement of the symptoms of ARS and return to normal functioning when used as monotherapy or as an adjunct to antibiotics.
Antibiotics for acute rhinosinusitis in adults.
Assessing the effects of antibiotics versus placebo or no treatment in adults with acute rhinosinusitis in ambulatory care settings found that antibiotics can shorten time to cure, but only 5 to 11 more people per 100 will be cured faster if they receive antibiotics instead of placebo orNo treatment.
Executive summary☆
Management update of acute bacterial rhinosinusitis and the use of cefdinir.
  • J. Gwaltney
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2002
Clinical diagnosis of ABRS is based on obtaining a history of a cold or influenza-like illness that is no better or worse after >/=7 days and a 10-day course of treatment with an antimicrobial effective against resistant S pneumoniae and H influenzae is recommended.
Acute Rhinosinusitis
This pharmacoeconomic review of antibacterial use in acute rhinosinusitis shows the need for improvement in the quality of the studies feeding economic analyses, but suggests that huge financial interests are at stake.
Management of acute bacterial rhinosinusitis
Treatment is generally for 10 to 14 days and for at least 7 days beyond the time of substantial improvement in symptoms, and when the disease persists despite treatment, or is complicated by potential intracranial or orbital extension, CT is the preferred imaging modality.
Acute community-acquired bacterial sinusitis: continuing challenges and current management.
  • M. Sande, J. Gwaltney
  • Medicine
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2004
Accurate diagnosis can select patients who would benefit most from antimicrobial use, and Antimicrobial agents should be selected on the basis of local resistance patterns, and their spectrum of activity should cover the common bacterial pathogens, including resistant strains.


Principles of Appropriate Antibiotic Use for Treatment of Acute Respiratory Tract Infections in Adults: Background, Specific Aims, and Methods
The need to improve Antibiotic Prescription for Acute Respiratory Infections and the clinical impact of antibiotic-resistant S. pneumoniae on morbidity, mortality, and health care costs in children or adults is highlighted.
Sinusitis in the common cold☆☆☆★★★
Adjunct effect of loratadine in the treatment of acute sinusitis in patients with allergic rhinitis
H1‐blockers are often added to the standard treatment of acute sinusitis, but this is not supported by a controlled study, so loratadine in addition to standard therapy was found to improve the control of some symptoms of Sinusitis.
Etiology and antimicrobial therapy of acute maxillary sinusitis.
Clinical and bacteriologic responses to all three regimens were good, and the efficacy of therapy with orally administered ampicillin, amoxicillin, or trimethoprim-sulfamethoxazole was evaluated by a repeat sinus puncture and culture.
The end of antibiotic treatment in adults with acute sinusitis-like complaints in general practice? A placebo-controlled double-blind randomized doxycycline trial.
Data from this study indicate that doxycycline does not add to the effectiveness of decongestive nose drops and steam inhalation in treating acute sinusitis-like complaints in general practice adults.
Intranasal flunisolide spray as an adjunct to oral antibiotic therapy for sinusitis.
Use of symptoms and signs to diagnose maxillary sinusitis in general practice: comparison with ultrasonography.
The five symptoms algorithm would improve diagnostic accuracy of general practitioners, but incorrect and uncertain diagnoses cannot be avoided.
Predictors of antibiotic prescribing for nonspecific upper respiratory infections, acute bronchitis, and acute sinusitis. An UPRNet study. Upper Peninsula Research Network.
Patients who were older than 18 years, sick for more than 14 days, and seen in urgent care clinics were more likely to receive antibiotics and patients expected antibiotics if they perceived that the drug had helped with similar symptoms in the past.
Infectious rhinosinusitis in adults: classification, etiology and management. International Rhinosinusitis Advisory Board.
  • V. Lund
  • Medicine
    Ear, nose, & throat journal
  • 1997
The definitions and classification of infectious rhinosinusitis are discussed, together with a summary of current views on its etiology and management, resulting from the deliberations of an international group of clinicians with a special interest in this area.