Principle of the bark of Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune responses.

@article{Mori1995PrincipleOT,
  title={Principle of the bark of Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune responses.},
  author={Hiroshi Mori and Masahiro Fuchigami and Nobumasa Inoue and H. Nagai and Akihide Koda and Itsuo Nishioka and Kuniaki Meguro},
  journal={Planta medica},
  year={1995},
  volume={61 1},
  pages={45-9}
}
Previously we have isolated the quaternary base alkaloids, magnoflorine and phellodendrine, from Phellodendri Cortex (cortex of Phellodendron amurense Rupr., Rutaceae) as the biologically active principles to suppress local graft-versus-host (GvH) reactions in mice. In this paper, we focus on phellodendrine. Phellodendrine suppressed local semisyngeneic GvH reactions and systemic allogeneic GvH reactions in X-ray irradiated recipient mice. Phellodendrine also suppressed the induction phase of… CONTINUE READING

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