Principal component analysis of minimal excitatory postsynaptic potentials.

  title={Principal component analysis of minimal excitatory postsynaptic potentials.},
  author={A. V. Astrelin and Maxim V Sokolov and Thomas Behnisch and Klaus G. Reymann and Leon L. Voronin},
  journal={Journal of neuroscience methods},
  volume={79 2},
'Minimal' excitatory postsynaptic potentials (EPSPs) are often recorded from central neurones, specifically for quantal analysis. However the EPSPs may emerge from activation of several fibres or transmission sites so that formal quantal analysis may give false results. Here we extended application of the principal component analysis (PCA) to minimal EPSPs. We tested a PCA algorithm and a new graphical 'alignment' procedure against both simulated data and hippocampal EPSPs. Minimal EPSPs were… CONTINUE READING


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Estimate of the variance of the quantal size in excitatory synapses of area CA 1 of hippocampal slices

  • LL Voronin, NV Ivanov, U Kuhnt
  • Neurophysiology
  • 1993
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