Principal component analysis of PiB distribution in Parkinson and Alzheimer diseases.

@article{Campbell2013PrincipalCA,
  title={Principal component analysis of PiB distribution in Parkinson and Alzheimer diseases.},
  author={Meghan C. Campbell and Joanne Markham and Hubert Flores and Johanna M. Hartlein and Alison M. Goate and Nigel J. Cairns and Tom O. Videen and Joel S. Perlmutter},
  journal={Neurology},
  year={2013},
  volume={81 6},
  pages={520-7}
}
OBJECTIVE To use principal component analyses (PCA) of Pittsburgh compound B (PiB) PET imaging to determine whether the pattern of in vivo β-amyloid (Aβ) in Parkinson disease (PD) with cognitive impairment is similar to the pattern found in symptomatic Alzheimer disease (AD). METHODS PiB PET scans were obtained from participants with PD with cognitive impairment (n = 53), participants with symptomatic AD (n = 35), and age-matched controls (n = 67). All were assessed using the Clinical… CONTINUE READING
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