Primus inter pares (First among equals)

2 nature structural biology • volume 8 number 1 • january 2001 A curious feature of DNA polymerases is that they cannot combine two deoxynucleosidetriphosphates (dNTPs) to start DNA chains, but must instead initiate DNA synthesis with a hydroxyl group on a preformed primer. This mechanistic peculiarity complicates several aspects of DNA replication and… CONTINUE READING

2 Figures & Tables