Primordial genetics: phenotype of the ribocyte.

  title={Primordial genetics: phenotype of the ribocyte.},
  author={Michael Yarus},
  journal={Annual review of genetics},
The idea that the ancestors of modern cells were RNA cells (ribocytes) can be investigated by asking whether all essential cellular functions might be performed by RNAs. This requires isolating suitable molecules by selection-amplification when the predicted molecules are presently extinct. In fact, RNAs with many properties required during a period in which RNA was the major macromolecular agent in cells (an RNA world) have been selected in modern experiments. There is, accordingly, reason to… CONTINUE READING