Primordial carbonylated iron-sulfur compounds and the synthesis of pyruvate.

  title={Primordial carbonylated iron-sulfur compounds and the synthesis of pyruvate.},
  author={George D. Cody and Nabil Z. Boctor and Timothy R. Filley and Robert M. Hazen and J. H. Scott and A. Sharma and Hatten S. Yoder},
  volume={289 5483},
Experiments exploring the potential catalytic role of iron sulfide at 250 degrees C and elevated pressures (50, 100, and 200 megapascals) revealed a facile, pressure-enhanced synthesis of organometallic phases formed through the reaction of alkyl thiols and carbon monoxide with iron sulfide. A suite of organometallic compounds were characterized with ultraviolet-visible and Raman spectroscopy. The natural synthesis of such compounds is anticipated in present-day and ancient environments… Expand
Assaying the catalytic potential of transition metal sulfides for abiotic carbon fixation
Abstract A suite of nickel, cobalt, iron, copper, and zinc containing sulfides are assayed for the promotion of a model carbon fixation reaction with relevance to local reducing environments of theExpand
Catalytic Nickel-Iron-Sulfur Clusters: From Minerals to Enzymes
The geochemical theory of the origin of life proposes that primordial, pre-biotic reactions were carried out in a metal-sulfide-rich environment similar to that found near hot springs at the oceanExpand
Natural Pyrrhotite as a Catalyst in Prebiotic Chemical Evolution
The results showed that pyrrhotite, under simulated hydrothermal conditions, could catalyze the pyruvate synthesis from lactate and that a dynamic system formed by coupling iron metal and iron-sulfur species in an electrochemical cell could promote carbon fixation from thioacetate esters. Expand
Geochemical Connections to Primitive Metabolism
Many microorganisms make extensive use of transition metal sulfide clusters in their metabolic chemistry. Similarly, transition metal sulfide minerals, e.g., pyrrhotite and pyrite, have the potentialExpand
The Interface Between the Biological and Inorganic Worlds: Iron-Sulfur Metalloclusters
Complex iron-sulfur metalloclusters form the active sites of the enzymes that catalyze redox transformations of N2, CO, and H2, which are likely components of Earth's primordial atmosphere. AlthoughExpand
▪ Abstract The history of the theory and experimental evidence that the natural catalytic and reactive qualities of transition metal sulfides are linked to primitive metabolism is reviewed. In theExpand
Biomimetic phosphoryl transfer catalysed by iron(II)-mineral precipitates
Iron(II) minerals have been found to catalyse the formation of pyrophosphate from activated phosphate compounds and inorganic phosphate at near neutral pH in water. Iron(II) phosphate catalyses theExpand
Chemistry and the hydrogenases.
The reversible reduction protons to dihydrogen: 2H+ + 2e [symbol: see text] H2 is deceptively the simplest of reactions but one that requires multistep catalysis to proceed at practical rates. HowExpand
Origin of the Reductive Tricarboxylic Acid (rTCA) Cycle-Type CO2 Fixation: A Perspective
The feasibility of non-enzymatic cofactor-assisted drive of the rTCA reactions in the primitive Earth environments, particularly focusing on the acetyl-CoA conversion to pyruvate is discussed, supporting the theory of an autotrophic origin of life from primordial carbon assimilation within a sulfide-rich hydrothermal vent. Expand
A radical solution for the biosynthesis of the H‐cluster of hydrogenase
This work presents a mechanistic scheme for hydrogenase H‐cluster biosynthesis in which both carbon monoxide and cyanide ligands can be derived from the decomposition of a glycine radical. Expand


Activated acetic acid by carbon fixation on (Fe,Ni)S under primordial conditions.
In experiments modeling the reactions of the reductive acetyl-coenzyme A pathway at hydrothermal temperatures, it was found that an aqueous slurry of coprecipitated NiS and FeS converted CO and CH3SHExpand
Nature's carbonylation catalyst: Raman spectroscopic evidence that carbon monoxide binds to iron, not nickel, in CO dehydrogenase.
A bimetallic mechanism is proposed, in which carbon monoxide binds to an iron atom and is subsequently attacked by a methyl group on a nearby nickel atom, forming an acetyl ligand, which is then transferred to coenzyme A. Expand
Iron-sulfur clusters: nature's modular, multipurpose structures.
Iron-sulfur clusters now rank with such biological prosthetic groups as hemes and flavins in pervasive occurrence and multiplicity of function. Expand
Iron-sulfur proteins
Structures and Reactions of Iron-Sulfur Protein Clusters and Their Synthetic Analogs (J. Berg and R. Holm). Iron-Sulfur Proteins: The Problem of Determining Cluster Type (W. Orme-Johnson and N.Expand
Biological Hydrogen Production: Not So Elementary
Many organisms metabolize hydrogen gas by means of an enzyme called hydrogenase. The nature of the catalytic sites in the hydrogenases has long been a subject of conjecture and debate. In theirExpand
X-ray crystal structure of the Fe-only hydrogenase (CpI) from Clostridium pasteurianum to 1.8 angstrom resolution.
A three-dimensional structure for the monomeric iron-containing hydrogenase (CpI) from Clostridium pasteurianum was determined, providing insights into the mechanism of biological hydrogen activation and has broader implications for [Fe-S] cluster structure and function in biological systems. Expand
A molecular view of microbial diversity and the biosphere.
  • N. Pace
  • Biology, Medicine
  • Science
  • 1997
Over three decades of molecular-phylogenetic studies, researchers have compiled an increasingly robust map of evolutionary diversification showing that the main diversity of life is microbial,Expand
Perspectives on archaeal diversity, thermophily and monophyly from environmental rRNA sequences.
Phylogenetic analysis of ribosomal RNA sequences obtained from uncultivated organisms of a hot spring in Yellowstone National Park reveals several novel groups of Archaea, many of which diverged fromExpand
Origin and evolution of biological energy conversion
Anion receptors and guests structure molecular dynamics thermodynamics physico-chemical properties of solid anion complexes photochemistry catalysis applications.
Popping Rocks and Lava Tubes from the Mid-Atlantic Rift Valley at 36° N
DURING the 1972 Midlante cruise of the RV Jean Charcot to survey a limited area of the rift valley south of the Azores, a dredge (CH-DR11) was taken at a depth of 1,360 fathoms in a depression nearExpand