Primitive neuroectodermal tumors of childhood. An approach to therapy.

  title={Primitive neuroectodermal tumors of childhood. An approach to therapy.},
  author={Patricia K. Duffner and Michael Enrique Cohen and Reid R. Heffner and Arnold I. Freeman},
  journal={Journal of neurosurgery},
  volume={55 3},
Primitive neuroectodermal tumors are found in the cerebrum of children and young adults. The are clinically highly malignant and have rapid course from diagnosis to death. Their microscopic pathology reveals 90% to 95% nondifferentiation, frequent mitoses, and small dark cells with no observable cytoplasm. This paper discusses the treatment of three children with this tumor with a combination of surgery irradiation, and combination chemotherapy. The results of this approach are compared with… CONTINUE READING


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