Primitive nervous systems: action of aminergic drugs and blocking agents on activity in the ventral nerve cord of the flatworm Notoplana acticola.

@article{Keenan1979PrimitiveNS,
  title={Primitive nervous systems: action of aminergic drugs and blocking agents on activity in the ventral nerve cord of the flatworm Notoplana acticola.},
  author={Larry Keenan and Harold Koopowitz and Kerry L. Bernardo},
  journal={Journal of neurobiology},
  year={1979},
  volume={10 4},
  pages={
          397-407
        }
}
Electrically evoked activity in the submuscular ventral longitudinal nerve cords of Notoplana acticola is depressed by GABA and glycine in the presence of high magnesium concentrations. This inhibition occurs with 0.001--0.01 millimolar concentrations of these putative aminergic neurotransmitters and is reversible when washed out. The action of GABA and glycine was reversed nonspecifically by picrotoxin, bicuculline, and strychnine. PTZ (Pentylenetetrazole) was shown to mimic the effects that… 
Primitive nervous systems: electrophysiology of inhibitory events in flatworm nerve cords.
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Depression and the subsequent lifting of the inhibition occur in Ringer baths containing either normal sea water or equal mixtures of sea water and isotonic MgCl2.
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Primitive nervous systems: electrophysiology of inhibitory events in flatworm nerve cords.
TLDR
Depression and the subsequent lifting of the inhibition occur in Ringer baths containing either normal sea water or equal mixtures of sea water and isotonic MgCl2.
Primitive nervous systems: electrical activity in ventral nerve cords of the flatworm, Notoplana acticola.
TLDR
The diffuse potential appears to be conducted throughout the plexus but preferential conducting pathways occur around lesions, and both diffuse and fast potentials show facilitation of response to repeated stimulation.
Primitive nervous systems. Control and recovery of feeding behavior in the polyclad flatworm, Notoplana acticola.
TLDR
Feeding behavior in Notoplana acticola involves a series of local responses which are under central control, and Worms are still able to ingest food in the absence of the brain using local reflexes.
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TLDR
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