Primitive complement system--recognition and activation.

  title={Primitive complement system--recognition and activation.},
  author={Teizo Fujita and Yuichi Endo and Masaru Nonaka},
  journal={Molecular immunology},
  volume={41 2-3},
The complement system, composed of more than 30 serum and cell surface components, is collaborating in recognition and elimination of pathogens as a part of both the innate and acquired immune systems. The two collagenous lectins, mannose-binding lectin (MBL) and ficolins, are one of the pattern recognition molecules acting in innate immunity and upon recognition of the pathogens, they trigger the activation of the lectin complement pathway through attached serine proteases (MASPs). A similar… CONTINUE READING


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