Priming with a DNA vaccine delivered by attenuated Salmonella typhimurium and boosting with a killed vaccine confers protection of chickens against infection with the H9 subtype of avian influenza virus.

@article{Pan2009PrimingWA,
  title={Priming with a DNA vaccine delivered by attenuated Salmonella typhimurium and boosting with a killed vaccine confers protection of chickens against infection with the H9 subtype of avian influenza virus.},
  author={Zhiming Pan and Xiaoming Zhang and Shizhong Geng and Ningning Cheng and Lin Yan Sun and Beibei Liu and Jinlin Huang and Xinan Jiao},
  journal={Vaccine},
  year={2009},
  volume={27 7},
  pages={1018-23}
}
Control of the circulation of H9 low-pathogenic avian influenza virus (LPAIV) is a major concern for both animal and public health. To improve vaccine efficacy against H9 LPAIV, we have utilized a novel prime-boost vaccination strategy. Specific-pathogen free (SPF) chickens were first orally immunized with a hemagglutinin (HA) DNA vaccine delivered by attenuated Salmonella typhimurium, followed by boosting with a killed avian influenza (AI) vaccine. Chickens in this combined vaccination group… CONTINUE READING
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Enhanced stability of plamid pcDNA 3 . 1 + within Salmonella typhimurium by downregulation of the ampicillin resistance gene expression

  • XM Zhang, XA Jiao, LH Tang, ZM Pan, YL Yin, XF Liu
  • Microbiology
  • 2007

Cloning of HA gene of H9N2 subtype avian influenza virus and immune protection test of its DNA vaccine

  • HX He, XM Qin, QZ Zhang, Y Tang, LY Liu, CX Zheng
  • Prog Biochem Biophys
  • 2004
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