Priming of systemic and local delayed-type hypersensitivity responses by feeding low doses of ovalbumin to mice.

@article{Lamont1989PrimingOS,
  title={Priming of systemic and local delayed-type hypersensitivity responses by feeding low doses of ovalbumin to mice.},
  author={A G A Lamont and Allan McI Mowat and Delphine M. V. Parrott},
  journal={Immunology},
  year={1989},
  volume={66 4},
  pages={595-9}
}
We have examined the effects on both systemic and intestinal immunity of feeding different doses of ovalbumin (OVA) to mice. A single feed of doses of more than 1 mg OVA produced significant suppression of subsequent delayed-type hypersensitivity (DTH) and IgG antibody responses. Feeding 100 micrograms-1 mg OVA had no net effect on systemic immunity, but mice fed 10-50 micrograms OVA had consistently enhanced systemic DTH responses when immunized subsequently with OVA in adjuvant. Oral… CONTINUE READING

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