Priming of intracellular calcium stores in rat CA1 pyramidal neurons.

  title={Priming of intracellular calcium stores in rat CA1 pyramidal neurons.},
  author={Min Pyo Hong and William N Ross},
  journal={The Journal of physiology},
  volume={584 Pt 1},
Repetitive synaptic stimulation evokes large amplitude Ca(2+) release waves from internal stores in many kinds of pyramidal neurons. The waves result from mGluR mobilization of IP(3) leading to Ca(2+)-induced Ca(2+) release. In most experiments in slices, regenerative Ca(2+) release can be evoked for only a few trials. We examined the conditions required for consistent release from the internal stores in hippocampal CA1 pyramidal neurons. We found that priming with action potentials evoked at 0… CONTINUE READING

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