Prime-boost immunization strategies for infectious diseases.

  title={Prime-boost immunization strategies for infectious diseases.},
  author={Helen McShane},
  journal={Current opinion in molecular therapeutics},
  volume={4 1},
  • Helen McShane
  • Published 2002 in Current opinion in molecular therapeutics
New vaccination strategies that induce the cellular arm of the immune response are needed for the development of effective prophylactic and therapeutic vaccines against a number of intracellular pathogens. DNA vaccines, recombinant viral vectors and recombinant proteins are all effective antigen delivery systems for inducing cellular immunity; however, when used alone, the levels of specific responses they induce are low. Prime-boost immunization strategies involve using two different vaccines… CONTINUE READING

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