Primate models of dystonia

  title={Primate models of dystonia},
  author={Dominique Guehl and Emmanuel Cuny and Imad Ghorayeb and Thomas Michelet and Pierre Burbaud},
  journal={Progress in Neurobiology},
Several models of dystonia have emerged from clinical studies providing a comprehensive explanation for the pathophysiology of this movement disorder. However, several points remain unclear notably concerning the specific role of brainstem, basal ganglia nuclei and premotor cortex. We review data collected in sub-human primate to see whether they might provide new insights into the pathophysiology of dystonia. As in human patients, lesions of the putamen induce dystonia, as well as… CONTINUE READING


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