Primate defensins
@article{Lehrer2004PrimateD, title={Primate defensins}, author={R. Lehrer}, journal={Nature Reviews Microbiology}, year={2004}, volume={2}, pages={727-738} }
Defensins are endogenous, cysteine-rich antimicrobial peptides that contribute to host defence against bacterial, fungal and viral infections. There are three subfamilies of defensins in primates: α-defensins are most common in neutrophils and Paneth cells of the small intestine; β-defensins protect the skin and the mucous membranes of the respiratory, genitourinary and gastrointestinal tracts; and θ-defensins, which are expressed only in Old World monkeys, lesser apes and orangutans, are… CONTINUE READING
329 Citations
Mammalian defensins in the antimicrobial immune response
- Biology, Medicine
- Nature Immunology
- 2005
- 1,057
- PDF
β-Defensins: Multifunctional Modulators of Infection, Inflammation and More?
- Biology, Medicine
- Journal of Innate Immunity
- 2012
- 217
A pocket guide to explorations of the defensin field.
- Biology, Medicine
- Current pharmaceutical design
- 2007
- 9
- PDF
Defensin-Barbed Innate Immunity: Clinical Associations in the Pediatric Population
- Medicine
- Pediatrics
- 2010
- 34
References
SHOWING 1-10 OF 211 REFERENCES
Mammalian defensins in immunity: more than just microbicidal.
- Biology, Medicine
- Trends in immunology
- 2002
- 657
Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins
- Biology, Medicine
- FEBS letters
- 1993
- 426
Defensin‐6 mRNA in human Paneth cells: implications for antimicrobia peptides in host defense of the human bowel
- Biology, Medicine
- FEBS letters
- 1993
- 324
- PDF
Roles of antimicrobial peptides such as defensins in innate and adaptive immunity
- Biology, Medicine
- Annals of the rheumatic diseases
- 2003
- 360
- PDF
RK-2: A Novel Rabbit Kidney Defensin and Its Implications for Renal Host Defense
- Chemistry, Medicine
- Peptides
- 1998
- 23
Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1998
- 366
- PDF
Minidefensins: antimicrobial peptides with activity against HIV-1.
- Biology, Medicine
- Current pharmaceutical design
- 2003
- 54
Cathelicidins - a family of multifunctional antimicrobial peptides
- Biology, Medicine
- Cellular and Molecular Life Sciences CMLS
- 2003
- 380