Primate defensins

@article{Lehrer2004PrimateD,
  title={Primate defensins},
  author={R. Lehrer},
  journal={Nature Reviews Microbiology},
  year={2004},
  volume={2},
  pages={727-738}
}
  • R. Lehrer
  • Published 2004
  • Medicine
  • Nature Reviews Microbiology
  • Defensins are endogenous, cysteine-rich antimicrobial peptides that contribute to host defence against bacterial, fungal and viral infections. There are three subfamilies of defensins in primates: α-defensins are most common in neutrophils and Paneth cells of the small intestine; β-defensins protect the skin and the mucous membranes of the respiratory, genitourinary and gastrointestinal tracts; and θ-defensins, which are expressed only in Old World monkeys, lesser apes and orangutans, are… CONTINUE READING
    329 Citations
    Defensins as anti-infective and immunomodulatory agents
    • 2
    Mammalian defensins in the antimicrobial immune response
    • 1,057
    • PDF
    β-Defensins: Multifunctional Modulators of Infection, Inflammation and More?
    • 217
    Defensins in innate antiviral immunity
    • 398
    • PDF
    A pocket guide to explorations of the defensin field.
    • M. Selsted
    • Biology, Medicine
    • Current pharmaceutical design
    • 2007
    • 9
    • PDF
    β-Defensins in the Fight against Helicobacter pylori
    • 22
    • PDF
    6 Defensins in Ulcerative Colitis
    • PDF
    Review: Defensins and cathelicidins in lung immunity
    • 148
    Antimicrobial peptides important in innate immunity
    • 196

    References

    SHOWING 1-10 OF 211 REFERENCES
    Mammalian defensins in immunity: more than just microbicidal.
    • 657
    α-Defensins in the gastrointestinal tract
    • 127
    Mouse neutrophils lack defensins.
    • 217
    • PDF
    Roles of antimicrobial peptides such as defensins in innate and adaptive immunity
    • 360
    • PDF
    Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family.
    • 366
    • PDF
    Minidefensins: antimicrobial peptides with activity against HIV-1.
    • 54
    Cathelicidins - a family of multifunctional antimicrobial peptides
    • 380