Primate defensins

@article{Lehrer2004PrimateD,
  title={Primate defensins},
  author={R. Lehrer},
  journal={Nature Reviews Microbiology},
  year={2004},
  volume={2},
  pages={727-738}
}
  • R. Lehrer
  • Published 2004
  • Medicine
  • Nature Reviews Microbiology
Defensins are endogenous, cysteine-rich antimicrobial peptides that contribute to host defence against bacterial, fungal and viral infections. There are three subfamilies of defensins in primates: α-defensins are most common in neutrophils and Paneth cells of the small intestine; β-defensins protect the skin and the mucous membranes of the respiratory, genitourinary and gastrointestinal tracts; and θ-defensins, which are expressed only in Old World monkeys, lesser apes and orangutans, are… Expand
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