Primate and feline lentivirus vector RNA packaging and propagation by heterologous lentivirus virions.

@article{Browning2001PrimateAF,
  title={Primate and feline lentivirus vector RNA packaging and propagation by heterologous lentivirus virions.},
  author={Matthew T Browning and Russell D Schmidt and Kathy A Lew and Tahir A. Rizvi},
  journal={Journal of virology},
  year={2001},
  volume={75 11},
  pages={5129-40}
}
Development of safe and effective gene transfer systems is critical to the success of gene therapy protocols for human diseases. Currently, several primate lentivirus-based gene transfer systems, such as those based on human and simian immunodeficiency viruses (HIV/SIV), are being tested; however, their use in humans raises safety concerns, such as the generation of replication-competent viruses through recombination with related endogenous retroviruses or retrovirus-like elements. Due to the… CONTINUE READING
28 Citations
47 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Lentiviral vectors, p. 47–60

  • L. Naldini, I. M. Verma
  • 1999

Similar Papers

Loading similar papers…