Primary tissue failure in pericardial heart valves.

  title={Primary tissue failure in pericardial heart valves.},
  author={David J. Wheatley and John Sheridan Fisher and I J Reece and Tom J Spyt and P. Breeze},
  journal={The Journal of thoracic and cardiovascular surgery},
  volume={94 3},
A number of centers have recorded a significant incidence of primary tissue failure with the standard Ionescu-Shiley pericardial valve. In most cases severe regurgitation was caused by leaflet tears adjacent to the edge of the cloth-covered stent. Our early clinical experience (up to 4 years' follow-up) with two new pericardial valves (Ionescu-Shiley low-profile and Hancock pericardial valves) has shown that primary tissue failure also occurs in these new valves. In vitro accelerated fatigue… CONTINUE READING