Primary structure of the vitamin K‐dependent part of prothrombin

@article{Magnusson1974PrimarySO,
  title={Primary structure of the vitamin K‐dependent part of prothrombin},
  author={S. Magnusson and L. Sottrup-jensen and Torben Elleb{\ae}k Petersen},
  journal={FEBS Letters},
  year={1974},
  volume={44}
}
  • S. Magnusson, L. Sottrup-jensen, Torben Ellebæk Petersen
  • Published 1974
  • Biology, Medicine
  • FEBS Letters
  • The biosynthesis of normal prothrombin is vitamin K-dependent [ 11. During dicoumarol treatment a prothrombin is produced [2,3] which can neither be adsorbed to barium citrate nor bind calcium ions [4] and therefore is not activated in the normal Ca’+, phospholipid systems. One reason for determining the primary structure of prothrombin has been to find the structural modification caused by vitamin K. Analyses of carbohydrate and amino acid compositions as well as N-terminal sequences of normal… CONTINUE READING

    Topics from this paper.

    The vitamin K-dependent carboxylase.
    • 65
    • Open Access
    DICOUMAROL‐INDUCED PROTHROMBINS
    • 19

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 12 REFERENCES
    Immunochemical determination of human prothrombin.
    • 40
    FEBS Letters 22,257-260
    • 1972