Primary structure of porcine plasminogen. Isolation and characterization of CNBr-fragments and their alignment within the polypeptide chain.

@article{Brunisholz1981PrimarySO,
  title={Primary structure of porcine plasminogen. Isolation and characterization of CNBr-fragments and their alignment within the polypeptide chain.},
  author={Ren{\'e} A. Brunisholz and E E Rickli},
  journal={European journal of biochemistry},
  year={1981},
  volume={119 1},
  pages={15-22}
}
The single polypeptide chain of native plasminogen (molecular weight approx. 90000) after CNBr-cleavage and gel filtration (Sephadex G-75) yielded a high molecular weight core fraction of fragments linked by disulfide bridges and three fragments of lower molecular weight (N-terminal and C-terminal CNBr-fragments and dodecapeptide). From the reduced and S… CONTINUE READING