Primary structure of insulin from the african lungfish, Protopterus annectens.

@article{Conlon1997PrimarySO,
  title={Primary structure of insulin from the african lungfish, Protopterus annectens.},
  author={J Michael Conlon and James E. Platz and Per. F. Nielsen and Hubert Vaudry and M. Teran De Vallarino},
  journal={General and comparative endocrinology},
  year={1997},
  volume={107 3},
  pages={
          421-7
        }
}
Among the extant Sarcopterygii, the interrelationship between the Dipnoi (lungfishes), Actinistia (coelacanths), and Tetrapoda (tetrapods) is controversial. Insulin has been purified from an extract of the pancreas of the African lungfish Protopterus annectens and its primary structure established as A-chain, Gly-Ile-Val-Glu-Gln-Cys-Cys-His-Lys-Pro10-Cys-Ser-Leu- Tyr -Glu-Leu-Glu-Asn-Tyr-Cys20-Asn-Val-Pro; and B-chain, Ala-Val-Leu-Asn-Gln-His-Leu-Cys-Gly-Ser10-His-Leu-Val- Glu- Ala-Leu-Tyr-Leu… CONTINUE READING
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