Primary structure of human pepsinogen gene.

  title={Primary structure of human pepsinogen gene.},
  author={Kazuhiro Sogawa and Yoshiaki Fujii-Kuriyama and Yu Mizukami and Yoshikazu Ichihara and Kiyohiro Takahashi},
  journal={The Journal of biological chemistry},
  volume={258 8},
A recombinant clone, which covers the pepsinogen gene in a single insert, has been isolated by screening a library of human genomic DNA, using a swine pepsinogen cDNA as a probe. Sequence analysis of coding DNA segments of the clone revealed that the pepsinogen gene occupies approximately 9.4-kilobase pairs of the genomic DNA and is separated into nine exons by eight introns of various lengths. The predicted amino acid sequence of human pepsinogen consists of 373 residues and is 82% homologous… CONTINUE READING
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