Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors.

@article{Hammond1987PrimarySO,
  title={Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors.},
  author={Geoffrey L. Hammond and C. L. Smith and Ing Swie Goping and D. Alan Underhill and M J Harley and Jaume Reventós and Neal A. Musto and Glen L. Gunsalus and C. Wayne Bardin},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 15},
  pages={
          5153-7
        }
}
  • G. Hammond, C. Smith, C. Bardin
  • Published 1 August 1987
  • Biology
  • Proceedings of the National Academy of Sciences of the United States of America
We have isolated and sequenced cDNAs for corticosteroid binding globulin (CBG) prepared from human liver and lung mRNAs. Our results indicate that CBG mRNA is relatively abundant in the liver but is also present in the lung, testis, and kidney. The liver CBG cDNA contains an open reading frame for a 405-amino acid (Mr 45,149) polypeptide. This includes a predominantly hydrophobic, leader sequence of 22 residues that precedes the known NH2-terminal sequence of human CBG. We, therefore, predict… 

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References

Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Laboratory

  • 1982