Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis

@article{Compton1992PrimarySO,
  title={Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis},
  author={D. Compton and I. Szilak and D. Cleveland},
  journal={The Journal of Cell Biology},
  year={1992},
  volume={116},
  pages={1395 - 1408}
}
From a collection of monoclonal antibodies that specifically bind to various parts of the mitotic apparatus in human cells (1991. J. Cell Biol. 112: 1083-1097), two (1F1 and 1H1) recognize a greater than 200- kD intranuclear protein that associates with the spindle immediately upon nuclear envelope breakdown and progresses down the spindle microtubules to concentrate ultimately at the pericentrosomal region. At the completion of anaphase this protein dissociates from the spindle microtubules… Expand
NuMA is required for the proper completion of mitosis
NuMA is required for the proper completion of mitosis.
Localization of NuMA protein isoforms in the nuclear matrix of mammalian cells.
Role of NuMA in vertebrate cells: review of an intriguing multifunctional protein.
NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization
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References

SHOWING 1-10 OF 59 REFERENCES
Nucleocytoplasmic sorting of macromolecules following mitosis: fate of nuclear constituents after inhibition of pore complex function.
Centrophilin: a novel mitotic spindle protein involved in microtubule nucleation
CENP-B: a major human centromere protein located beneath the kinetochore
...
1
2
3
4
5
...