Primary structure and topological analysis of a skeletal muscle-specific junctional sarcoplasmic reticulum glycoprotein (triadin).

@article{Knudson1993PrimarySA,
  title={Primary structure and topological analysis of a skeletal muscle-specific junctional sarcoplasmic reticulum glycoprotein (triadin).},
  author={Charles M. Knudson and K K Stang and Carolyn R. Moomaw and Clive A. Slaughter and Kevin P Campbell},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 17},
  pages={12646-54}
}
The primary amino acid sequence for a highly abundant junctional sarcoplasmic reticulum glycoprotein (triadin) has been deduced from the cDNA sequence. Based on both biochemical analysis and the predicted amino acid sequence we suggest that this protein is an intrinsic membrane glycoprotein containing a single transmembrane domain that separates the protein into cytoplasmic and luminal domains. The cytoplasmic domain is proposed to contain the amino-terminal 47 amino acids. The remainder of the… CONTINUE READING