Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons


ODORANT signal transduction occurs in the specialized cilia of the olfactory sensory neurons. Considerable biochemical evidence now indicates that this process could be mediated by a G protein-coupled cascade using cyclic AMP as an intracellular second messenger1. A stimulatory G protein α subunit is expressed at high levels in olfactory neurons and is… (More)
DOI: 10.1038/347184a0


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