Primary sclerosing cholangitis is associated with a distinct phenotype of inflammatory bowel disease.

@article{Boonstra2012PrimarySC,
  title={Primary sclerosing cholangitis is associated with a distinct phenotype of inflammatory bowel disease.},
  author={Kirsten Boonstra and Karel Johannes van Erpecum and Karin M J van Nieuwkerk and Joost P H Drenth and Alexander C. Poen and B J M Witteman and Hans Are Tuynman and Ulrich Beuers and Cyriel Y. Ponsioen},
  journal={Inflammatory bowel diseases},
  year={2012},
  volume={18 12},
  pages={
          2270-6
        }
}
BACKGROUND Primary sclerosing cholangitis (PSC) is strongly associated with inflammatory bowel disease (IBD). The aim of this study was to assess the IBD phenotype associated with PSC in a large well-phenotyped population-based PSC cohort using endoscopic and histopathologic criteria. METHODS PSC cases were identified and ascertained, fulfilling well-established criteria, in 39 hospitals in a geographically defined region of The Netherlands. IBD location was recorded according to the Montreal… CONTINUE READING

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Risk factors for primary sclerosing cholangitis.

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