Primary sclerosing cholangitis

@article{Hirschfield2013PrimarySC,
  title={Primary sclerosing cholangitis},
  author={Gideon M. Hirschfield and Tom Hemming Karlsen and Keith D. Lindor and David H. Adams},
  journal={The Lancet},
  year={2013},
  volume={382},
  pages={1587-1599}
}
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311 Citations

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References

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Primary sclerosing cholangitis is a chronic cholestatic liver disease caused by progressive inflammatory destruction of intra hepatic and extrahepatic bile ducts, and ultimately cirrhosis, and affects primarily young to middle-aged men.
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TLDR
There is an increased incidence of both acute and chronic rejection, hepatic artery thrombosis and biliary stricturing in PSC patients undergoing liver transplantation.
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Primary sclerosing cholangitis is a chronic cholestatic liver disorder that most commonly affects middle-aged men, and patients with PSC have reduced survival rates compared with the general population.
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