Primary role of the HLA class II DRB1*0301 allele in Graves disease.

@article{Zamani2000PrimaryRO,
  title={Primary role of the HLA class II DRB1*0301 allele in Graves disease.},
  author={Mohammed Zamani and Marijke Spaepen and Marie Bex and R Bouillon and J. J. Cassiman},
  journal={American journal of medical genetics},
  year={2000},
  volume={95 5},
  pages={432-7}
}
The association of the Graves disease (GD) with HLA DR3 and DQA1*0501 in Caucasians has been described previously. From these studies it could not be determined whether one specific locus was primarily involved. Using a case-control study design, we have examined the role of HLA class II gene polymorphisms in the predisposition for GD in a group of Belgian subjects. We demonstrated that both DRB1*0301 and DQA1*0501 alleles conferred significant susceptibility in the DRB1*0301-DQA1*0501… CONTINUE READING

From This Paper

Topics from this paper.
24 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Similar Papers

Loading similar papers…