Primary prostate stromal cells modulate the morphology and migration of primary prostate epithelial cells in type 1 collagen gels.


The effects of human primary prostatic stromal cells on the migration and morphogenesis of human prostatic epithelial cells, derived from tumor or benign prostatic hyperplasia tissue, were studied using a three-dimensional coculture system. Epithelial cells from tumor or benign tissue migrated efficiently into collagen gels populated with stromal cells from… (More)


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