Primary prophylaxis with fluconazole against systemic fungal infections in HIV-positive patients.

@article{Nightingale1992PrimaryPW,
  title={Primary prophylaxis with fluconazole against systemic fungal infections in HIV-positive patients.},
  author={Stephen Nightingale and Santiago Cal and Dolores M. Peterson and S D Loss and B. Gamble and Dorothy M Watson and C P Manzone and Jennifer E Baker and J D Jockusch},
  journal={AIDS},
  year={1992},
  volume={6 2},
  pages={191-4}
}
OBJECTIVE To investigate the efficacy of fluconazole prophylaxis against systemic fungal infections in HIV-positive patients. DESIGN Open label treatment compared with historical controls. SETTING Patients were seen at the Parkland Memorial Hospital HIV Clinic, Dallas, Texas, USA between 1 March 1990 and 28 February 1991. PATIENTS, PARTICIPANTS Three hundred and thirty-seven historical controls were followed for 157 patient-years, and 329 fluconazole-treated patients for 145 patient-years… CONTINUE READING