Primary prophylaxis of overt hepatic encephalopathy in patients with cirrhosis: an open labeled randomized controlled trial of lactulose versus no lactulose.

@article{Sharma2012PrimaryPO,
  title={Primary prophylaxis of overt hepatic encephalopathy in patients with cirrhosis: an open labeled randomized controlled trial of lactulose versus no lactulose.},
  author={Praveen Sharma and Barjesh Chander Sharma and Amit Agrawal and Shiv Kumar Sarin},
  journal={Journal of gastroenterology and hepatology},
  year={2012},
  volume={27 8},
  pages={1329-35}
}
BACKGROUND AND AIM Development of overt hepatic encephalopathy (HE) is associated with poor prognosis in patients with cirrhosis. Lactulose is used for the treatment of HE. There is no study on the prevention of overt HE using lactulose in patients who never had HE earlier. METHODS Consecutive cirrhotic patients who never had an episode of overt HE were randomized to receive lactulose (Gp-L) or no lactulose (Gp-NL). All patients were assessed by psychometry (number connection test [NCT-A and… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

Recent developments in the diagnosis and treatment of covert/minimal hepatic encephalopathy.

Expert review of gastroenterology & hepatology • 2016
View 10 Excerpts
Highly Influenced

Effects of lactulose and silymarin on liver enzymes in cirrhotic rats.

Canadian journal of physiology and pharmacology • 2017
View 1 Excerpt

Hepatic encephalopathy

Gastroenterology report • 2017

Hepatic encephalopathy: what the multidisciplinary team can do

Journal of multidisciplinary healthcare • 2017
View 1 Excerpt

Similar Papers

Loading similar papers…