Primary progressive aphasia with focal neuronal achromasia.

@article{Lippa1991PrimaryPA,
  title={Primary progressive aphasia with focal neuronal achromasia.},
  author={Carol F Lippa and Rony Cohen and Thomas R. Smith and David A Drachman},
  journal={Neurology},
  year={1991},
  volume={41 6},
  pages={882-6}
}
We describe the clinical, radiologic, neuropsychological, and neuropathologic features of a 69-year-old man with a 3-year history of progressive transcortical expressive aphasia. Neuropsychological testing showed progressive dysfunction of expressive language. Neuropathologic examination demonstrated focal cortical degeneration involving the left superior frontal gyrus, with swollen achromasic neurons and no evidence of Alzheimer's disease, Pick's disease, Creutzfeldt-Jakob disease, Lewybody… CONTINUE READING