Primary neuroendocrine carcinoma of the skin expresses tyrosinase mRNA: detection by a specific nested PCR technique.

@article{Alegre1997PrimaryNC,
  title={Primary neuroendocrine carcinoma of the skin expresses tyrosinase mRNA: detection by a specific nested PCR technique.},
  author={Marta Alegre and Lu{\'i}s Puig and Ramiro Carre{\~n}o and M. A. Argany Baiget and Emilo Del R{\'i}o and Maria T. Fern{\'a}ndez-Figueras and J M de Moragas},
  journal={Dermatology},
  year={1997},
  volume={194 4},
  pages={
          334-7
        }
}
BACKGROUND Tyrosinase transcripts have been identified in a wide range of normal organs and neoplasms such as cutaneous nevi, breast carcinomas, liposarcomas and schwannomas. The cells responsible for these positive results have not been accurately identified yet, but they might correspond to either fully differentiated melanocytes, melanocytic precursors or cells bearing potential for melanocytic differentiation. OBJECTIVE To assess the expression of tyrosinase mRNA in surgical resection… CONTINUE READING