Primary myocardial involvement in systemic sclerosis: evidence for a microvascular origin.

@article{Allanore2010PrimaryMI,
  title={Primary myocardial involvement in systemic sclerosis: evidence for a microvascular origin.},
  author={Yannick Allanore and Christophe Meune},
  journal={Clinical and experimental rheumatology},
  year={2010},
  volume={28 5 Suppl 62},
  pages={S48-53}
}
Systemic sclerosis (SSc) is a connective tissue disease characterised by widespread vascular lesions and fibrosis of the skin and internal organs. Cardiac involvement is recognised as a poor prognostic factor when clinically evident. Primary myocardial involvement is common in SSc. Increasing evidence strongly suggests that myocardial involvement is related to repeated focal ischaemia leading to myocardial fibrosis with irreversible lesions. Reproducible data have shown that this relates to… CONTINUE READING

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