Primary myelofibrosis: A detailed statistical analysis of the clinicopathological variables influencing survival

@article{Rupoli1994PrimaryMA,
  title={Primary myelofibrosis: A detailed statistical analysis of the clinicopathological variables influencing survival},
  author={Serena Rupoli and L. Da Lio and S. Sisti and G. Campanati and Aldo Salvi and Maria Feliciana Brianzoni and Silvia D'Amico and A. Cinciripini and Pietro Leoni},
  journal={Annals of Hematology},
  year={1994},
  volume={68},
  pages={205-212}
}
In the present study we analyzed the prognostic significance of several clinical, hematological, and histological parameters recorded at diagnosis in a consecutive series of 72 patients with primary myelofibrosis (PMF). Univariate analysis showed that the most significant indicators of poor survival were the following: age greater than 60, splenomegaly, anemia (hemoglobin > 10 g/dl), leukopenia (WBC<4×109/l or leukocytosis >14x109/l), and any of these histological features: adipose tissue and… CONTINUE READING
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