Primary immune deficiencies with defects in neutrophil function.

  title={Primary immune deficiencies with defects in neutrophil function.},
  author={Mary Dinauer},
  journal={Hematology. American Society of Hematology. Education Program},
  volume={2016 1},
  • Mary Dinauer
  • Published 2016 in
    Hematology. American Society of Hematology…
Immune deficiencies resulting from inherited defects in neutrophil function have revealed important features of the innate immune response. Although sharing an increased susceptibility to bacterial and fungal infections, these disorders each have distinctive features in their clinical manifestations and characteristic microbial pathogens. This review provides an update on several genetic disorders with impaired neutrophil function, their pathogenesis, and treatment strategies. These include… CONTINUE READING