Primary hyperhidrosis

@article{Kaufmann2003PrimaryH,
  title={Primary hyperhidrosis
},
  author={Horacio Kaufmann and Daniela Saadia and Charlene Polin and Stephen Hague and Amanda Singleton and Andrew Singleton},
  journal={Clinical Autonomic Research},
  year={2003},
  volume={13},
  pages={96-98}
}
Abstract. Primary hyperhidrosis is a neurogenic disorder of unknown cause characterized by excessive sweating in the palmar surface of the hands, armpits, groin and feet. In the course of a therapeutic trial for primary hyperhidrosis, 62 % of patients reported a positive family history. Examination of these pedigrees demonstrated a sibling recurrence risk of λs = 29–48 and an offspring recurrence risk of λo = 41–68 indicating that hyperhidrosis can be an inherited condition. The pattern of… 
Treatment of Secondary Hyperhidrosis -A report of three cases-
TLDR
Three cases of secondary hyperhidrosis following systemic disease and trauma, which were treated with systemic or topical anticholinergics were experienced.
[Hyperhidrosis-aetiopathogenesis, diagnosis, clinical symptoms and treatment].
  • J. Wohlrab, B. Kreft
  • Medicine
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
  • 2018
TLDR
Primary hyperhidrosis is a complex neuropathic dysregulation with a genetic predisposition and is diagnosed when patients show pathologic sweating patterns and excessive sweating for at least 6 months and fulfill at least four of the following criteria.
Treatment of Hand Eczema Caused by Hyperhidrosis
TLDR
Treatment modalities for hyperhidrosis include topical antiperspirants, iontophoresis, botulinum toxin A injections, systemic anticholinergics, and surgical denervation of the thoracic sympathetic chain.
Plantar Hyperhidrosis: An Overview.
  • T. Vlahovic
  • Medicine
    Clinics in podiatric medicine and surgery
  • 2016
Diagnosis and treatment of primary hyperhidrosis.
TLDR
The most common form of focal hyperhidrosis is excessive sweating localized mainly on the surface of palms or feet, which is associated with significant reduction of life quality resulting from impairment of daily activities, social interactions and professional activities.
Analysis of family history of palmoplantar hyperhidrosis in Japan
TLDR
Pedigree charts prepared based on data obtained by patient interviews suggested autosomal dominant inheritance in parent–child cases and the incidence of PPH in three generations was 13%.
Genetic disposition to primary hyperhidrosis: a review of literature
TLDR
It seems that primary hyperhidrosis is polygenically inherited, and considering the impairment, further data to understand the genetic etiology of the disease are needed.
Primary palmar hyperhidrosis locus maps to 14q11.2‐q13
TLDR
A linkage analysis of 11 families including 42 affected and 40 unaffected members using genome‐wide DNA polymorphic markers to identify the primary palmar hyperhidrosis locus supported that one of the PPH locus is assigned at minimum to about a 6‐cM interval between D14S1070 andD14S990 and at maximum to about about a 30‐ cM intervals between D 14S10 70 and D14 S70.
Botulinum Toxin for Hyperhidrosis
TLDR
Recent evidence suggests that botulinum toxin type A (BTX-A) injections into hyperhidrotic areas can considerably reduce focal sweating in multiple areas without major adverse effects, and BTx-A has therefore shown promise as a potential replacement for more invasive treatments after topical aluminum salts have failed.
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