Primary hyperaldosteronism: a missed diagnosis in 'essential hypertensives'?

  title={Primary hyperaldosteronism: a missed diagnosis in 'essential hypertensives'?},
  author={Mark Ashley Brown and H A Cramp and V C Zammit and Judith Ann Whitworth},
  journal={Australian and New Zealand journal of medicine},
  volume={26 4},
BACKGROUND It has been recognised recently that primary hyperaldosteronism may be more common than previously thought, the frequency of diagnosis being improved by screening using a plasma aldosterone concentration to renin activity ratio. AIMS To determine the frequency of primary hyperaldosteronism, screening with both plasma aldosterone to renin concentration (PRC) and activity (PRA) ratios, in normokalaemic subjects previously diagnosed as having essential hypertension. METHODS Plasma… CONTINUE READING


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