Primary hepatic neuroendocrine carcinoma in a child. Morphologic, immunocytochemical, and molecular biologic studies.

@article{Hsueh1993PrimaryHN,
  title={Primary hepatic neuroendocrine carcinoma in a child. Morphologic, immunocytochemical, and molecular biologic studies.},
  author={Chuen Hsueh and Xiaoda Tan and Frank Gonz{\'a}lez-Cruss{\'i}},
  journal={Cancer},
  year={1993},
  volume={71 8},
  pages={2660-5}
}
BACKGROUND Primary neuroendocrine tumor of the liver is uncommon, and virtually all reported patients with the tumor have been adults. Most of the tumors were carcinoids. The authors report an 8-year-old girl with primary hepatic neuroendocrine carcinoma. METHODS Histologic, ultrastructural, and immunocytochemical studies and Southern blot analysis of tumor N-myc DNA were performed in the patient. RESULTS Histologically, the tumor revealed a characteristic organoid pattern with a spectrum… CONTINUE READING

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