Primary hepatic follicular lymphoma : a case report and discussion of chemotherapy and favorable outcomes.

@article{Gomyo2007PrimaryHF,
  title={Primary hepatic follicular lymphoma : a case report and discussion of chemotherapy and favorable outcomes.},
  author={Hiroshi Gomyo and Yoshitoyo Kagami and Harumi Kato and Takakazu Kawase and Aya Ohshiro and Takashi Oyama and Yoshikazu Kamiya and Hirofumi Taji and Shigeo Nakamura and Michinori Ogura and Yasuo Morishima},
  journal={Journal of clinical and experimental hematopathology : JCEH},
  year={2007},
  volume={47 2},
  pages={
          73-7
        }
}
This report concerns a rare case of follicular lymphoma with features suggestive of primary hepatic lymphoma. At the disease onset, multiple nodular lesions in the liver and small para-aortic nodes were detected by abdominal magnetic resonance imaging without generalized lymphadenopathy. After careful observation for three months, lymphadenopathy was observed in the right occipital, para-aortic, and bilateral inguinal regions. The patient was treated with R-CHOP (rituximab, cyclophosphamide… 
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Primary liver lymphoma, even though rare, should be kept in differentials of multiple space occupying lesions of liver with no evidence of vascular invasion, especially if there is no associated lymphadenopathy or spleen involvement.
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TLDR
PHL should be considered in patients presenting with biliary obstruction in patients with radiological hepatic disease with normal serum alpha-fetoprotein and carcinoembryonic antigen levels, and elevated lactate dehydrogenase.
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