Primary graft dysfunction: definition, risk factors, short- and long-term outcomes.

@article{Lee2010PrimaryGD,
  title={Primary graft dysfunction: definition, risk factors, short- and long-term outcomes.},
  author={James C-M Lee and Jason D. Christie and Shaf H Keshavjee},
  journal={Seminars in respiratory and critical care medicine},
  year={2010},
  volume={31 2},
  pages={161-71}
}
Primary graft dysfunction (PGD) is a form of early lung graft dysfunction that is a major cause of early morbidity and mortality following lung transplantation. Survivors of PGD have decreased long-term lung function and an increased risk of developing bronchiolitis obliterans syndrome (BOS), a manifestation of chronic graft dysfunction. This article reviews the current definition, contributing factors, and guidelines for grading clinical PGD, as well as controversies surrounding them. The… CONTINUE READING
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